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Paschos, G
Novo Nordisk filed the NDA with the FDA on December 18, 2025
However, the DPP/DPPOS 21-year follow-up did not find a statistically significant reduction in major cardiovascular events with metformin versus placebo, though favorable trends in risk factors were observed
At the time, Lilly said the doses were also "priced at a 50% or greater discount compared to the list price of all other incretin (GLP-1) medicines for obesity." GLP-1 agonists are a class of Type 2 diabetes drugs that improve blood sugar control but may also lead to weight loss
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